All very vague. What is the actual strategic value in this? What would you be able to do that other spacefaring powers couldn't, and why would it matter in a strategic context?
"Some of their residents are literally untouchable"
It's trivially easy to stop shipments to the Moon. How long can a lunar biosphere last?
The trick is the ability to build everything and due to the cost of transporting stuff to the moon means CPU's are probably the last thing to be manufactured on the moon. So, once we start building chip fab's on the moon a lunar biosphere could last for millions of years.
"Some of their residents are literally untouchable"
It's trivially easy to stop shipments to the Moon. How long can a lunar biosphere last?