Lazarus seems amazing, and I'd love to write some software with it, but I can't get past the language. You generally do want to pick languages with a big ecosystem, as everything you might want will have already been written.
The difference between Python and Delphi isn't a bit more work, it's often the difference between "there's a library so I can make my thing" and "it would take way too long".
Pascal is a workhorse and to tame the horse takes a lot of skill and blind knowledge. And then when tamed, your horse is the best at the show.
I can't fault Pascal. It may not have every module ever like Python, it's syntax may feel archaic but the satisfaction and feel of producing a program with is fuzzy feeling great.
You can interface with existing libraries if you really want, you need to somehow expose a C ABI (be it via the library written in C, exposing an official C ABI or you writing a C bridge).
There is a 3rd party "Python-for-Lazarus" bridge[0] though for simple stuff you can use the python library directly:
The above uses the Tk library that comes with Python.
Also depending on what you want to do chances are there is already a Free Pascal library or existing bindings to a library written in another language. If not, if the library has a C header file you can use the h2pas utility that comes with FPC to make your own (though the generated code does need some modifications to work more often than not).
Of course all the above do assume you have knowledge of both Free Pascal and whatever you want to interface with, but at least as far as being able to access existing libraries is concerned, it should be possible - just with some hoops (and at that point it depends on how much you value whatever Lazarus provides over the effort involved in whatever library you want to use).
EDIT: and truth be told IMO the biggest roadblock with Lazarus isn't so much the language but that it is just not easy to learn most of that stuff (the core language and runtime library is decently documented but anything outside of that can be a hit and miss) and you basically need an almost arrogant attitude of "this is just dumb code, not magic, if it is technically possible i can figure out myself how to do it" :-P.
The difference between Python and Delphi isn't a bit more work, it's often the difference between "there's a library so I can make my thing" and "it would take way too long".