I'm curious what the world will look like when we are smart enough to become actionable with this information. Do we want to live in a world where someone in their garage can come up with a drug idea and send it to a PharmaFoundry to get their drug fabed and then sell it to people?
Correct me if I am wrong, but we have sequenced thousands of genomes but not human. We only have a handful where handful is < 1000) of full human genomes AFAIK. 1000 genomes isn't done yet AFAIK (their page on sequencing progress is down unfortunately). The human reference genome is a mishmash of multiple genomes. It also contains huge sections of chromosomes that are just N's (blank) because assemblers are unable to determine what goes there. On top of that, an actual human genome is not one genome. At they very least there are alleles which can be different from each other and in general there can be many genomes (cancer). Haploid sequencing is coming, hopefully soon, if SMRT really pans out but, in my opinion, to say our knowledge of even the sequence data in a human is adequate is a stretch (I'm not saying that you said that).
Correct me if I am wrong, but we have sequenced thousands of genomes but not human. We only have a handful where handful is < 1000) of full human genomes AFAIK. 1000 genomes isn't done yet AFAIK (their page on sequencing progress is down unfortunately). The human reference genome is a mishmash of multiple genomes. It also contains huge sections of chromosomes that are just N's (blank) because assemblers are unable to determine what goes there. On top of that, an actual human genome is not one genome. At they very least there are alleles which can be different from each other and in general there can be many genomes (cancer). Haploid sequencing is coming, hopefully soon, if SMRT really pans out but, in my opinion, to say our knowledge of even the sequence data in a human is adequate is a stretch (I'm not saying that you said that).