Yes! It's not even that much of a time investment; a short video [1] and some playing around can already give you a pretty good grip of common issues in 15 minutes.
Yes, that's not enough for properly evaluating the performance of what you're working on (screen readers differ far more than browsers do, and there's many different ways of navigating), but it helps form a mental model and to quickly encouter really egregious issues that e.g. make your entire project inaccessible with any screen reader.
[1] I think I used this one, to learn the general principles and to at least find the terms needed to find the shortcuts for my operating system: https://www.youtube.com/watch?v=5R-6WvAihms
Yes, that's not enough for properly evaluating the performance of what you're working on (screen readers differ far more than browsers do, and there's many different ways of navigating), but it helps form a mental model and to quickly encouter really egregious issues that e.g. make your entire project inaccessible with any screen reader.
[1] I think I used this one, to learn the general principles and to at least find the terms needed to find the shortcuts for my operating system: https://www.youtube.com/watch?v=5R-6WvAihms