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Cool, thanks for the reply. Are the approved use parenteral? Have you considered aptamers?


Yes, we are looking at IV, as others have done already clinically. We aren't looking at aptamers or other clever ways of binding small toxic biomolecules. I hope that other groups are!


This is a pretty interesting paper: https://stm.sciencemag.org/content/8/333/333ra50

Is there a chance that you are developing CD that target 7KC but at the end of the day, it dissolved chol-containing plaques inherently and that's where you'll derive the benefit from?




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