If you were asking, "Can I use an API to access data in my sheets from other apps/services?" - no, not today, but we'll add that at some point in the future.
Or if you were asking, "Can I query APIs to get data onto the spreadsheet?"
Yes, you can do that today in Quadratic with Fetch() in JS or Requests in Python.
I think you're not the only one that mentioned this omission, I'll throw in since it seems to be pretty poorly highlighted and has some surprising failure modes:
When you use the USER directive to set up a working user in Dockerfile, be explicit about UID and use the numeric UID.
What works 99% of the time is to use alpha username in the "USER" directive. You can get some surprising artifacts if the container runtime hits this rare bug[1]. There are likely several other great ways this can go wrong, as well.
Somewhere deep in the manual, it is suggested that you should only use a numeric UID, even though USER accepts an alphanumeric username most of the time, but if you look at container images built by OpenShift and other pro docker-ers, you will see they always do this with a numeric UID.