I just bought my ppu digitizer two days ago! Very excited to get that working.
There are a couple reasons you would go this route or classic nesrgb, and I was very tempted (I might still do a nesrgb on my other nes, if ppu digitizer goes well).
Primary one is lumacode is a digital signal that requires interpretation before it can be input into a tv. You can use the creator's rgb2hdmi which requires a raspberry Pi, or you can use a scaler like retrotink or ossc (pro). An RGB connection is standalone in many setups, and also works with scalers. If you want to interface with a CRT, lumacode doesn't immediately support that.
Additionally, ppudigitizer doesn't (directly) support multiple palletes. You are stuck with whatever your lumacode interpreter provides (though you could in theory change this yourself).
Only the vaccinated will preferentially evolve variants that are resistant to the vaccine. The vaccines are leaky, as evidenced by the recent outbreak in the Northeast. A saner strategy with leaky vaccines is to vaccinate the small population that is vulnerable and let the rest of the population of develop a natural herd immunity. Otherwise you are creating a fitness advantage to resistant strains.
This is not how it works, and "natural" herd immunity has never been a real concept in epidemiology - which it is clear you are speculating on without bothering to read about but should also be trivially obvious from the fact that until vaccines none of the vaccine preventable diseases ever went extinct on their own.
> Herd immunity is a form of indirect protection from infectious disease that can occur with some diseases when a sufficient percentage of a population has become immune to an infection, whether through vaccination or previous infections, thereby reducing the likelihood of infection for individuals who lack immunity.
Yes, and wikipedia is not the study of epidemiology.
Epidemiology as a field did not publish papers or study the idea of "natural" herd immunity till last year when politicians started throwing the term around and a whole lot of researcher's scrambled to see whether this insanity had any merit.
Of which the answer is what we already knew just spelled out more specifically: no, this doesn't actually happen in the wild without vaccines, because it's literally just spreading the virus. Viruses burn themselves out after infecting basically everyone, provided immunity is long lasting.
It is misleading though, since this definition is merely ‘flattening the curve’ for the rest of human life, and accepting the increased death rate every year. By contrast, a successful vaccination effort also ‘flattens the curve,’ but additionally substantially reduces the rate of deaths. The latter is what we have observed happen with high confidence in the vaccinated population for COVID: deaths of vaccinated individuals is much less common than for unvaccinated (back of napkin math seems to currently be somewhere between 100-1000 to 1 across most age ranges)
I don't think when people talked about herd immunity they meant that the coronavirus would be wiped out, just that it'd get the replication rate down to a manageable level. Just like those diseases that vaccines wiped out, the young would always be at risk of being infected. In this case though, the young (babies excepted) are also fairly protected from it getting serious.
NMN is not approved yet but you can buy them online from reputed sellers. Check their 3rd party testing. Dont buy from Amazon/Ebay, some of independent tests came up with 0% NMN (so what are they?)
Vitamin B3 also increases NMN level and is a precursor to NMN.
It's probably better to just take nicacin (B3) as its safer until NMN is proven to be safe for human in longer doses. NMN is too large molecule to enter cells so anyway its broken down before it can be absorbed.
B3 is a precursor to NAD+ but you also need some amino acids to make it.
Taking NMN directly also had some health issues that were discovered recently. More importantly it can speed up cancer if you are predisposed to it or if you already have undiagnosed cancer.
as far as I can remember, one of the treatments of cancer is removing nmn from body.
You can buy niagen, which has nicotinamide riboside (NR), which is basically the same thing - the goal is to increase NAD+ in the mitochondria. NR is an immediate precursor to NMN which is NR with an added phosphate group, which makes NMN itself unlikely to enter any cell directly.
Religions house many people fearful of what is happening in their lives, the lives of their loved ones. They want explanations for why their expectations and needs are not met. Is it surprising that the powerful would leverage that fear?
Funny how the Hebrew and Greek words for fear have so many other meanings, and yet the church has taught but one for so long when considering the "fear of God".
Seems to contradict "perfect love casts out all fear". Perhaps we would all be better off if we understood "wisdom begins with the awe of God" as the preferred intention.
> It's not a great move to assume that conservatives are dumb, racist, and unsophisticated.
I don't love labels, but I don't think "conservatives" are simply any of those things.
This isn't an original thought, but I think they are mostly afraid of losing their community if they change their mind.
Fear of disconnection is innate and biological. When my trump supporting friends say "I believe it" to somebody suggesting that the Capitol Hill rioters were antifa pretending to be trump supporters, their lack of interest in challenging their own beliefs stems from the risk incurred with disagreeing with their friends and loved ones.
This effect is so strong that our brains give hits of dopamine whenever our beliefs are confirmed. We are not weird to change our minds.
So no. "Conservatives" aren't dumb. Just like the rest of us, they biologically afraid of social disconnection. And all that shouting across the isle makes it harder for them to see "progressives" accepting them.
I'm a conservative and it has zero to do with identifying with a certain community or concern about being rejected by them.
Republican candidates are more likely to vote on issues I care about in a way that aligns with my values. That alignment is far from perfect, but it's a lot better than it would be with a Democrat, especially a progressive Democrat.
That's why I typically vote Republican, sometimes begrudgingly. Has nothing to do with belonging to a community. In fact, the communities I am a part of rarely discuss politics. We discuss values that inform our politics, but the politics themselves are secondary.
I have absolutely no fear of social disconnection due to my political views. If I was to suddenly start voting democratic, no one in my closest circles would even need to know.
And I care nothing about whether progressives accept me. I simply have very different values and don't believe where they want our culture and country to move is healthy. So, I don't support them in elections. How they feel about me is irrelevant.
Take the bathroom ban in North Carolina. It got polarized into a trans/non-trans fight, where all people who supported separate gender bathrooms were dumb, transphobic people. The polarization marginalizes a legitimate argument:
Women should not have to walk into a rest stop restroom at night during a road trip, see a man, and then think about whether or not he should be there. And a man should not have the right to be there because he "identifies" as a woman when he really doesn't and is just a pervert in a rest stop bathroom. But with a new law, it then has to go through the court to prove whether he had the right to be there. The damage is done way before that day shows up.
The polarization and simplification meant that democrats couldn't vote against this because it became associated with transphobia. A vote to keep separate bathrooms would mean being canceled and losing their seat. The republicans were villainized, but they have a fairly decent point. Obviously, no one should feel uncomfortable using the restroom, but what unintended consequences come with the law? You can say perverts in bathrooms is an edge case, but I'd argue a trans person being denied a restroom is also an edge case.
Starbucks arguably came up with the best answer with gender-indifferent restrooms that are single occupancy, but this isn't always scalable. There are single occupancy family restrooms in many places, so if someone truly feels unsafe to use a restroom, they could use those. These were options that were put into place without laws.
It's not "right or wrong" or "black and white" on nearly any issue we face today. It's complex, and federal laws, given they impact 330 million Americans, have more unintended consequences than laws enacted at the local or state level. And that's what the republican, conservative party wants - less "big laws" with fewer unintended consequences in favor of state laws that allow people to govern themselves at the local level. It's also why any vote to undermine a State's right to certify its election results flies in the face of conservatism.
I'm not the OP but I know several voters who seem to match the OP's sentiment:
1. Abortion is simply the legally sanctioned killing of helpless human beings. I know _many_ single issue voters who begrudgingly voted for trump because of this.
2. Climate change denialism is pretty much anti common sense. Anyone who completely ignores the issue stinks of corruption.
Many complex topics with a lot of gray areas are often framed in soundbites that are extreme - you're either pro-life or pro-choice. You're either pro-Trump or anti-Trump.
A person can be a staunch supporter of women's rights to liberty and the pursuit of happiness but draw the line at a woman's right to end another's life. The "all-or-nothing" approach pushes people into one of two camps that each holds extreme opposing views, and it's happening across the different issues we face today.
Votes in a functioning democratic society are anonymous. You can vote one way and tell folks you voted another to "fit in".
But people become who they hang around. So if they are in a vacuum and they only hear that the election was stolen, anything else is fake news, and the president is telling them this, they may seriously believe that democracy is under siege.
Amp it up with technology echo chambers and reinforcing behaviors and you wind up with extreme situations where a group of people storms the capitol.
It's when people don't believe they can end up with similarly distorted views on a topic that they are susceptible to this themselves. This is along the lines of the Lucifer Effect.
Specifically for the pandemic, I think there are many things. Post on a neighborhood community board (e.g. on reddit, nextdoor, etc) offering food (sanitized). Get toys for underprivileged children. Or, write letters to strangers in elderly care homes and/or prisons, who may not get to see family or have anyone who thinks about them.
I'd argue he never experienced anything that terrible. I can totally relate to wondering whether even another hour was doable, and no, being alive just for the sake of being alive in those moments is not worth it. I guess I've always been hopeful even in the worst of times that things will get better (they always do) and that's the only thing that makes those stretches workable.
There are a couple reasons you would go this route or classic nesrgb, and I was very tempted (I might still do a nesrgb on my other nes, if ppu digitizer goes well).
Primary one is lumacode is a digital signal that requires interpretation before it can be input into a tv. You can use the creator's rgb2hdmi which requires a raspberry Pi, or you can use a scaler like retrotink or ossc (pro). An RGB connection is standalone in many setups, and also works with scalers. If you want to interface with a CRT, lumacode doesn't immediately support that.
Additionally, ppudigitizer doesn't (directly) support multiple palletes. You are stuck with whatever your lumacode interpreter provides (though you could in theory change this yourself).